Tattoo release week
It’s hard for me to believe it, but Tattoo will be released this Thursday, May 6, both in the US and UK. This journey began over two years ago when I published an opinion paper in JAMA...
Category: Alzheimer’s disease
To sleep, perchance to dream
A number of studies have previously noted that people with dementia tend to sleep less than those without dementia. The question has been what is cause and what is effect? Does getting less sleep promote the...
A walk in the woods with Jack
Jack and I are committed to getting our 10-12,000 steps of walking per day. As I describe in Tattoo, the evidence is very strong that regular, aerobic exercise reduces the risk of getting Alzheimer’s, and...
Evaluating new advances in Alzheimer’s research: separating hype from fact
We all know that Alzheimer’s is an enormous problem. Thousands of researchers around the world are tirelessly searching for clues that might lead to a solution – how to slow or prevent Alzheimer’s. Reports of...
Sea foam
I love to walk. Every day my dog Jack and I work on our 10,000 steps either on the neighborhood streets or the nearby trails of Forest Park when we are home in Portland or...
A glimmer of hope from a new anti-amyloid monoclonal antibody: closing the barn door before the horses get out
As I have mentioned in a previous post, the beta-amyloid plaques of Alzheimer’s disease can be seen in the brain up to 20 years before the onset of cognitive decline. The amyloid hypothesis holds...
Lost in the fog of Alzheimer’s
Getting literally lost in the fog is a terrifying experience. It happened to me about thirty years ago while sailing in the San Juan Islands, an archipelago that lies between Vancouver Island in British Columbia...
Face blindness during a pandemic
Recently while out walking my dog Jack, I encountered a blond woman pushing a toddler in a stroller while walking her dog. I stopped to chat asking her how old her son was now and...
Loss of smell in Covid-19 and Alzheimer’s
Two days ago, I read a fascinating article in the New York Times by restaurant critic Tejal Rao about her sudden loss of smell due to Covid-19 last December. “I noted that moment as...
A primer on amyloid, tau and PET scans
In retrospect, my first symptom of Alzheimer’s disease occurred in 2006 when I first noticed a decrease in my sense of smell. About a year later I started having illusory odors that were always the...
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