The cost of aducanumab
When donepezil (Aricept) was approved in 1996, it was the first tolerable drug available to treat the cognitive symptoms of Alzheimer’s disease. I remember being shocked that the price was so high, about $120...
Monthly Archive: June 2021
Aducanumab controversies
Yesterday I participated in a panel discussion regarding recommendations for use of aducanumab, now called by the proprietary name Aduhelm, in the treatment of Alzheimer’s disease. The conference, Dialogue: Current Perspectives on Aducanumab, was sponsored...
A day on Bald Mountain
Yesterday my friend Henry and I hiked about 7 miles in and out on a segment of the Timberline Trail in the Mt. Hood Wilderness. The Timberline Trail is a 41.2-mile loop that circumnavigates...
Sensory triggers of memory
Marcel Proust famously wrote in his semi-autobiographical novel Remembrance of Things Past published in 1913 how the smell and taste of a tea-soaked madeleine cake evoked the childhood memory of breakfast with his Aunt Léonie. The...
FDA approves aducanumab
Today the FDA approved the use of Biogen’s anti-amyloid monoclonal antibody aducanumab for treating early-stage Alzheimer’s disease. I have mixed feelings about this approval. As someone living with early-stage Alzheimer’s who participated in the aducanumab...
Eagle eyes
During the thirty-five years we have lived in Portland, Oregon, sightings of bald eagles have become much more common. The species is thriving. It is still a thrill to see one soaring over our house or...
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