A neurologist's personal battle against Alzheimer's disease
Today Biogen announced the changes highlighted in yellow below in the prescribing information for Aduhelm, recently approved for treatment of Alzheimer’s disease. There were several problems with the FDA’s initial brand label authorizing use...
I’ve always loved the Fourth of July. Fireworks were a big part of the holiday for as long as I can remember. When I was a child, we would usually spend most of the summer...
I read Lisa Genova’s first book, Still Alice, in 2009, long before I had any inkling that I was on the path to Alzheimer’s. I was busy in my practice as a general neurologist, and...
When donepezil (Aricept) was approved in 1996, it was the first tolerable drug available to treat the cognitive symptoms of Alzheimer’s disease. I remember being shocked that the price was so high, about $120...
Yesterday I participated in a panel discussion regarding recommendations for use of aducanumab, now called by the proprietary name Aduhelm, in the treatment of Alzheimer’s disease. The conference, Dialogue: Current Perspectives on Aducanumab, was sponsored...
Yesterday my friend Henry and I hiked about 7 miles in and out on a segment of the Timberline Trail in the Mt. Hood Wilderness. The Timberline Trail is a 41.2-mile loop that circumnavigates...
Marcel Proust famously wrote in his semi-autobiographical novel Remembrance of Things Past published in 1913 how the smell and taste of a tea-soaked madeleine cake evoked the childhood memory of breakfast with his Aunt Léonie. The...
Today the FDA approved the use of Biogen’s anti-amyloid monoclonal antibody aducanumab for treating early-stage Alzheimer’s disease. I have mixed feelings about this approval. As someone living with early-stage Alzheimer’s who participated in the aducanumab...
During the thirty-five years we have lived in Portland, Oregon, sightings of bald eagles have become much more common. The species is thriving. It is still a thrill to see one soaring over our house or...
Due to a series of unforeseen events this week, both of our children living in Portland needed additional help caring for their children, our four grandchildren. There is nothing I like better than spending...
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