In my opinion, people with two copies of the APOE-4 allele should not be given anti-amyloid monoclonal antibodies
So far, three anti-amyloid monoclonal antibodies have been approved in the US by the FDA for treatment of dementia or mild cognitive impairment (MCI) caused by Alzheimer’s disease: aducanumab, lecanemab, and most recently donanemab....
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